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Blood Stem Cell Donation Process Explained
About DATRI :
DATRI is a Not-for-Profit organization that was founded in 2009 with a mission to save lives of those suffering from life threatening fatal blood disorders like Blood Cancer, Thalassemia, Leukaemia, Aplastic Anaemia, Sickle Cell Anaemia etc…
DATRI Founders :
Dr. Nezih Cereb and Dr. Soo Young Yang are the founders of Histogenetics, a laboratory which performs high resolution HLA (Human Leukocyte Antigen) typing. HLA is used to determine a tissue match between a patient and a healthy donor. For many suffering from a fatal blood disorder (like Leukemia, Thalassemia and other diseases) a Bone Marrow or a Blood Stem Cell Transplant from an Unrelated Blood Stem Cell Donor…
1. How does bone marrow donation help in saving lives?
There are 25 out of 100 chances that a person can find a matched bone marrow donor from within the family. Majority patients reach out unrelated donors to save their lives. The probability of finding the right match from Unrelated Blood Stem Cell Donor is 1 in 10,000 as it depends on how closely the HLA typing matches between a donor and a patient.
2. How does a blood stem cell donor registry work in India?
A Blood Stem Cell Donor’s registry works to help Blood Disorders patients and give them a second chance to survive. Some registries are non-profits like DATRI, while others might not. These registries compile and store the details of registered donors. When there is a requirement for a patient, the registry runs a search to find the unrelated HLA matched donor for the patient.
3. What is the minimum age for blood stem cell donation?
Donors between 18 years to 50 years can come forward and register to be part of this noble cause.
4. How do we know Datri is a trustworthy organization?
DATRI is registered with the Government of India as a Section 8 organization and all monetary contributions towards DATRI are subject to 80G exemptions. DATRI has facilitated 668 donations in 10 years.
5. What makes DATRI’s Stem cell donor registry foundation the best?
DATRI is India’s largest Unrelated Blood Stem Cell Donors Registry which has 4+ Lakhs donor’s database. DATRI’s mission is to save lives of those suffering from life-threatening fatal blood cancers and disorders like Blood Cancer, Leukemia, Aplastic Anemia, Sickle Cell Anaemia, Thalassemia, etc.
6. Why is DATRI the top NGO in India?
DATRI works with integrity and transparency which makes us the top NGO in India.
DATRI is registered with the World Marrow Donors Association (WMDA) and is also listed in the Global Search Program, Bone Marrow Donors Worldwide Association (BMDW).
7. What is a bone marrow transplant & its process?
Bone marrow is the spongy tissue inside some of the bones, such as hip and thigh bones. It contains stem cells which can develop into the red blood cells that carry oxygen through the body, the white blood cells that fight infections, and the platelets that help with blood clotting. When a person’s body fails to produce these cells, the body requires a transplant to acquire new and healthy stem cells.
A bone marrow transplant is a procedure that replaces a person’s faulty bone marrow stem cells with new and healthy stem cells from related or unrelated HLA matched donor.
Before the transplant, the patient’s body is prepared. Any existing faulty marrow cells are killed through high doses of chemotherapy and possible radiation. This destroys the faulty stem cells that are present in the patient’s body and also suppresses body’s immune system so that it won’t attack the new stem cells after the transplant.
A healthy part of stem cells is then infused to the patient’s blood which gets carried to the bone tissues. This later develops to healthy and new marrow cells. The process works similar to blood transfusion.
8. How are bone marrow stem cells used for treatment?
The healthy stem cells are extracted from the donor’s bone marrow and then infused to the recipient. The infused cells travel through the bloodstream, reach the bone marrow and develop to healthy and new marrow cells.